Thursday, November 20, 2014

What's the Buzzzzzzzzzzzzzz?

So who here likes bees? I for one hate them, it has nothing to do with the bee itself but just with the simple fact that every time I have ever encountered one I was stung in some of the most unfortunate places… which leads to my justified hate, but a study done at Lund University has come to show the bees can be more than just a nascence, they can be a possible alternative to antibiotics. Lund University in Sweden found 13 lactic acid bacteria found in fresh honey, located in the in the bees honey stomach. Why are these 13 lactic acid bacteria so important? Well its simple, bees honey has been used against infections for millennium before we mass produced and sold it in stores. But now we look at the agents these bacteria’s contain and as the Lund University discovered bees honey can be used to help several server human wound pathogens such as MRSA, VRE and more. So when you see those little buggers remember they may sting you when bothered but there honey will be the things helping you one of these days.

Source:
Lund University. "Bacteria from bees possible alternative to antibiotics." ScienceDaily. ScienceDaily, 8 September 2014. <www.sciencedaily.com/releases/2014/09/140908093741.htm>.

Tuesday, October 21, 2014

Promising protein discovered for new drugs against tuberculosis

     

What is Tuberculosis? Short answer, a bacterial disease that effects the lungs. Now we hear of cases all the time about TB outbreaks or even just mild TB cases but we have not been able to find a way to prevent these cases/outbreaks… until now, hopefully? Leiden biologist Annemarie Meijer and her colleagues discovered a protein which triggers the process that the immune cells use to keep tuberculosis under control by breaking them down. This protein is DRAM1 and is hopefully the potential target towards new drugs. It was recently discovered that immune cells can destroy bacteria by what is essentially eating them. Which they do when there is a risk of a bacterial outbreak. In the study they infected zebra fish embryos with TB and DRAM1 and noticed that the DRAM1stimulates the process by which macrophages ‘eat’ the bacteria. Proving that DRAM1 will hopefully be used to prevent TB cases/outbreaks.  
 
Zebra fish.
Credit: Image courtesy of Leiden, Universiteit
Cite:
Leiden, Universiteit. "Promising protein discovered for new drugs against tuberculosis." ScienceDaily. ScienceDaily, 11 June 2014. <www.sciencedaily.com/releases/2014/06/140611131745.htm>.


How Ebola blocks immune system


Ebola Virus
Well just like the whole world is on watch for the Ebola outbreak so shall I! recently I read an article in which they discuss the process of how the Ebola virus blocks our immune system making it deadly, researchers at the Washington University School of Medicine identified one way the Ebola viruses dodges the bodies antiviral defenses, which they believe that having such an understanding could lead to new therapies. Basically in the article with the research that has been done they were able to tell that the Ebola protein VP24, binds to a host protein in our body signaling molecules in and out of the cell’s nucleus . The study concluded that the viral protein takes away the host protein’s ability to carry an important immune signal into the nucleus. The signal helps activate the immune system’s antiviral defenses, and blocking it. That is believed to be the big contribution factor why the virus is so deadly. Now if you were like me and didn’t understand what all that scientific mumbo-jumbo was talking about I can help you, the Ebola virus enters our body attaching to one of our cells and making the immune system believe it belongs there, it’s all about infiltration and disseat.

Cite:

DOE/Argonne National Laboratory. "How Ebola blocks immune system." ScienceDaily. ScienceDaily, 29 August 2014. <www.sciencedaily.com/releases/2014/08/140829135459.htm>.

Microbes help to battle infections



An artist’s representation of gut microbes promoting hematopoiesis.
Credit: Arya Khosravi and Wesley McBride/Caltech



When we think about microbes or even hear about them everyone jumps to the bad ones immediately and we all of the sudden relate each microbe to something bad rather than good, in fact anytime I hear about microbes I do that very exact thing… Upon my browsing and snooping around I was able to find a nice little article about some of the good microbes contribute to our bodies. In this article you read about Caltech professor of biology and biological engineering Sarkis Mazmanian, where his team are most interested in most bacteria and especially the ones already inside our bodies that actually keep us healthy. In a test done in March 12 the professor studied germ-free mice and healthy to study the gut bacteria and the effect it has on the mice immune system. To see how the mice would react to an infectious disease to them. In the healthy mouse they were able to bounce back after being infected, but when the germ-free mouse was infected due to the lack of immune cells the infection seems to be nearly fatal to the mouse until the mouse was introduced to normal gut microbes. Now after reading this study I have come to realize that if we don’t have our microbes in our stomachs or lack of microbes we have a lower immune cell count then that of a healthy human which is quite unfortunate.

Cite:

California Institute of Technology. "Microbes help to battle infection: Gut microbes help develop immune cells, study finds." ScienceDaily. ScienceDaily, 12 March 2014. <www.sciencedaily.com/releases/2014/03/140312132632.htm>.   

Wednesday, September 3, 2014

What's on your toothbrush that just might surprise you

Every morning when we get up we all have our own routine, mine happens to be when I get out of bed the first thing I do is go brush my teeth. As I do every day/week/month. I could not help but wonder what is on my toothbrush? and what is going in my mouth every morning when I brush me teeth? now that I've asked myself these questions the curiosity was killing me and I needed to find some form of research that was executed on the simple toothbrush to address these questions.

Staphylococci Bacteria
Based on the research done at the University of Alabama in May 6, 2014 Dr. Maria L. Geisinger, DDS, assistant professor of periodontology she states., "The oral cavity is home to hundreds of different types of microorganisms..." in her research Dr. Geisinger discover strains of  Staphylococci, coliforms, pseudomonads , yeasts, intestinal bacteria, and fecal germs these can all be found on your tooth brush. ways to prevent the bacteria from building up on your tooth brush are as followed, Don't share your toothbrush-Sharing of your toothbrush can lead to nasty bacteria that can cause dental decay and periodontal diseases. rinse your toothbrush in antibacterial mouth wash after each use, and replacing your toothbrush every three to four months.

Now that you know what can be on your toothbrush do you think you can still look at it the same?
I definitely can't...

David

Cite for my article:

University of Alabama at Birmingham. "Clean before you clean: What's on your toothbrush just might surprise you." ScienceDaily, May 6, 2014. www.sciencedaily.com/releases/2014/05/140506094439.htm.